Function Health vs Superpower vs OneTwenty (2026)

Price is no longer the reason to choose between these two. $349 against $365 is a rounding error on a year of healthcare, and both now include two blood draws through Quest with a comparable number of markers. Anyone still recommending Superpower because it is the cheap one is working from last year's pricing.

Superpower is the more complete product. It reads your Oura, Whoop and Apple Health data, sells you supplements at a member price, and prescribes, including GLP-1 and TRT, with medications billed separately. When a marker comes back wrong, something can actually happen on the platform.

Function is the more independent one. It has slightly more markers, clinician-written summaries that connect results to each other rather than listing them, and a physician who calls you directly if something urgent turns up. It sells you nothing, which is a real editorial advantage when the subject is what supplements you should take.

That last point is the honest tension. Superpower recommending a supplement it also sells you is convenient and conflicted at the same time. How much that bothers you is most of this decision.

Both memberships now include two draws, so for the first time the annual prices are directly comparable. Divide them out anyway, because it is the only number that survives a change in what each plan includes.

Superpower is about $8 cheaper per draw. Function is about half a cent cheaper per marker. Both differences are noise. If you are choosing on price you are choosing on nothing, which is the most useful thing this table has to say.

The number that is not noise is OneTwenty's. Four panels for $499 works out near $125 a draw, roughly 30 percent below either platform here, because the membership is built around testing quarterly rather than twice.

Function Health was founded in 2022 by Dr. Mark Hyman, a leading voice in functional medicine, and tech entrepreneur Jonathan Swerdlin. The pitch is early detection: monitor the markers a routine physical skips, rather than waiting for symptoms.

• 160+ lab tests a year across two draws: a first panel of 100+ markers, then a follow-up of 60+ markers three to six months later.
• Quest Diagnostics handles the draws at more than 2,000 locations, with no doctor's order needed. Results land in 7 to 10 business days, with a fuller clinician summary a couple of weeks after that.
• Clinician-written summaries that connect markers to each other rather than listing them, with diet, supplement and lifestyle suggestions.
• A physician calls you directly if anything urgent turns up. It is the best single feature either platform has and Superpower does not match it.
• Private AI Chat, Protocols and a biological age score, all added since launch alongside a price cut from $499 to $365.

Function's weakness used to be framed as testing twice a year instead of continuously. Now that Superpower also tests twice, the sharper criticism is what it does not do after the results: no supplements, no prescriptions, no wearable data. It tells you what is wrong and hands the problem back to you.

Superpower launched in 2023 out of Los Angeles as the cheap entry point to comprehensive testing. It is not the cheap one any more. At $349 with two draws, prescriptions and a supplement marketplace, it has moved from undercutting the category to competing inside it.

• 150+ biomarkers a year across two built-in draws: roughly 90 at baseline, then about 60 key markers retested later in the year, with results typically ready in about a week.
• A Superpower Score and a biological age, plus a Digital Twin view. More interpretation scaffolding than Function offers, though less written clinical judgement.
• Superpower AI, an in-app assistant trained on your results, with a human care team behind it.
• Wearable syncing with Oura, Whoop and Apple Health, and uploads of old lab PDFs so your history sits in one place.
• Supplements and prescriptions: one Marketplace with tabs for prescriptions, add-on tests and supplements, and prescription access that now includes GLP-1 and TRT, with medications priced separately from the membership.
• Add-on testing for gut health, environmental toxins, cancer screening and peptides, each billed on top.

The thing to watch on Superpower is the gap between the membership and the bill. $349 buys the testing and the platform. The supplements it recommends, the prescriptions it writes and the add-on panels it offers are all separate charges, and the whole design nudges you toward them. That is not dishonest, it is just a different business model from Function's, and it is worth knowing which one you are buying into.

Testing, price and frequency have converged. Three real differences are left.

• What happens when a marker is wrong. Function explains it and suggests. Superpower explains it, sells you the supplement and can write the prescription. This is the whole comparison in one line.
• Who is reading your results. Function writes clinician summaries and calls you if something is urgent. Superpower leans on Superpower AI, its in-app assistant, with a care team behind it. One is more thorough, the other is more available.
• Whether the advice is independent. Function does not sell supplements, so it has no reason to recommend one. Superpower does. Convenience and conflict arrive together.

• Do you want the platform to act, or to advise? Superpower acts. Function advises. Now that price and frequency match, this is the question that decides it.
• Do you already wear a tracker? If Oura, Whoop or Apple Health is already on your wrist, Function ignores it entirely and Superpower does not.
• Do you want supplement advice from someone who sells supplements? There is no right answer, but decide it deliberately rather than by accident.
• Do you live in New York or New Jersey? Get the real quoted price for both before comparing. Function publishes $600+; Superpower says only that pricing varies.
• How will you know if it worked? Two draws a year is one comparison a year. If that is not enough, neither of these is the answer.

Both earn 4 out of 5, and they now earn it for nearly the same reasons. Two draws, a Quest network, 150 to 160 markers, a dashboard with a biological age on it, and a price inside $16 of each other. The old shorthand, Superpower for budget and Function for depth, is dead.

What is left is a genuine difference in philosophy. Function is a diagnostic with a clinician attached: it reads your blood carefully, explains it in writing, calls you if something is wrong, and sells you nothing. Superpower is a health platform with a diagnostic inside it: it reads your wearable, writes the prescription, stocks the supplement, and makes its money on what happens next. Pick the one whose incentives you are comfortable with.

Both share the same ceiling. Two blood draws a year give you one comparison a year, which is enough to spot a problem and not enough to manage one. That is the case for testing quarterly instead. OneTwenty includes four panels at $499, about $125 a draw against roughly $175 and $183 here, with the supplement protocol and prescriptions built into the membership rather than sold on top. If you want your health managed across the year rather than checked twice, that is the one that covers the whole job.