The longevity and health-testing market has exploded, and the platforms in it are far less alike than their marketing suggests. Some run a single deep blood panel and hand you a clinician-reviewed report. Some are hormone-optimization clinics built around testosterone and peptides. Others are memberships that test you a few times a year and adjust your plan as you go. Picking the wrong one means paying for things you do not need, or missing the monitoring you do.
This guide compares five of the most notable options in 2026: OneTwenty, Geviti, Marek Health, Function Health, and Mito Health. We break down what each one costs, how often it tests you, what it actually does with the results, and who it is right for, so you can choose with clear eyes.
The Quick Verdict
OneTwenty vs Geviti vs Marek vs Function vs Mito: Comparison Chart
What each membership includes, checked against each company’s own website on October 7, 2026. “Not stated” means the site does not say; “Not listed” means the service is not offered on the site.
| What’s included | OneTwenty | Geviti | Marek Health | Function Health | Mito Health |
|---|---|---|---|---|---|
| Price | $499 / year ($749 in NY and NJ) | Free tier; Plus $127/mo, billed $1,529 / year | Program listed from $299 (billing period not stated), plus labs | $365 / year | $9 / month or $99 / year, plus labs at cost |
| What costs extra | Medications and supplements, billed as needed | Specialty tests, supplements and medications, at member prices | Every lab panel ($495 to $1,950), medications, supplements | MRI, CT, Galleri and other add-on tests | Every lab panel, consults, supplements |
| Lab draws a year | 4: 1 full panel, 3 targeted follow-ups | 2 on Plus; none on the free tier | Bought separately; required 6 to 12 weeks into treatment, then every 6 months | 2: an annual draw and a follow-up 3 to 6 months later | None included; you order panels as you want them |
| Biomarkers per draw | 95+ at baseline, 20 to 40 per follow-up | 104 | 80+, 100+ or 130+, by panel | 100+ at the annual draw, 60+ at the follow-up | 118, 138 or 166, by panel |
| Where blood is drawn | Nearby lab; at-home draw as an add-on | ✓ At home in many major metros, included on Plus | Quest location | Quest location, or an at-home draw you schedule | Quest location, or at home where available |
| Clinician access | Independent licensed providers through telehealth partners | Quarterly Longevity Specialist and clinician visits on Plus | 25-minute provider consult to start, then follow-ups | Clinicians review every result and flag issues | Clinician escalation in chat; 1:1 consults $39 per 30 min for members, $99 otherwise |
| Prescriptions (TRT / GLP-1 / HRT) | ✓ Testosterone, enclomiphene, GLP-1s through licensed providers | ✓ Peptides, HRT, GLP-1s on Plus, by state | ✓ TRT, GLP-1s, peptides | Not listed | Not listed |
| Supplements | ✓ Custom packs matched to your labs | ✓ Custom daily packs, at member prices | Sold separately from its own line | Not stated | Sold at member rates |
| Wearable / device data | ✓ 22 daily device metrics: Oura, Withings, Apple Health, Google Fit, CGMs | ✓ Sleep, HRV, recovery and glucose | Not stated | ✓ Connects supported apps | You can log wearable readings; sync not stated |
| AI & coaching | ✓ 24/7 AI Health Coach | Makor AI around the clock, plus a dedicated Longevity Specialist | Dedicated health coach with monthly check-ins; AI not stated | Private AI chat, and links to ChatGPT, Claude or Perplexity | Mito Concierge AI chat, year-round |
| Where it is available | ✓ Every state except RI | ✓ 47 states; not AK, RI or HI | Not in NY, NJ or RI | ✓ 48 states; not RI or HI; NY and NJ cost more | ✓ Lab testing in all states but RI and HI; NY and NJ cost more |
| HSA / FSA | ✓ | ✓ | Many clients pay with HSA or FSA, per Marek | ✓ | ✓ |
How Much Do These Platforms Cost?
These five do not price the same way, so comparing a single number is misleading. Mito Health is a $9 a month membership with the labs sold at cost, so what you pay depends on which panel you order. Function Health is a $365 yearly membership that includes two panels. Geviti now has a free tier for uploading existing labs, and its Plus membership is $127 per month billed annually ($1,529 a year), more on six-month billing, with prescription access included where state rules allow. Marek Health does not publish a monthly coaching fee: its treatment pages list the program from $299 without saying how often that is billed, and lab panels are bought separately, from $495 to $1,950 each. OneTwenty is $499 per year, with medications and supplements billed as needed.
The more useful question is not the sticker price but how often you are actually tested for it, because that determines whether you get a yearly snapshot or an ongoing picture of your health.
What Are These Platforms and How Do They Work?
A standard annual physical usually runs fewer than 20 markers, leaving out advanced cardiovascular risk markers like ApoB and Lipoprotein(a), full hormone and thyroid panels, inflammatory markers, and nutrient status. Every platform here tests those deeper markers. The differences come down to three things: how often they test you, whether they only test or also treat, and whether they fold in data from your wearables and daily life.
On one end, Mito Health and Function Health are testing-first platforms that give you a thorough panel and a plan. In the middle, Geviti adds a membership cadence and prescription access on higher tiers. Marek Health is a hormone-optimization specialist with the deepest diagnostics and a treatment menu to match. And OneTwenty sits at the far end, combining a full panel plus three targeted follow-ups a year with continuous wearable data, supplements, prescriptions, and a plan that is actively re-tuned every quarter.
The 5 Platforms, Reviewed
OneTwenty Review
Most platforms here test you once or twice a year and hand you a report. OneTwenty is built on the opposite premise: your own data should drive your plan, and that plan should keep changing as your body does. It runs one full panel, then three targeted follow-ups across the year, watches your wearables in between, and re-optimizes your protocol every 90 days based on what your numbers are actually doing. It is the only option in this comparison that combines deep testing with continuous monitoring and the ability to treat. It is in open beta and available in every state except Rhode Island, at $749 a year in New York and New Jersey.
- One full panel, then three targeted follow-ups: 95+ biomarkers at baseline, then 20 to 40 focused markers at each of three follow-up draws, four draws a year instead of one or two.
- 22 daily device metrics: Your wearable, smart scale, and blood pressure monitor stream sleep, HRV, heart rate, and body composition into one dashboard, so the gaps between labs are not blind spots.
- 24/7 AI Health Coach: It knows your labs, your wearable trends, and your protocol, and answers questions any time.
- Custom supplement delivery: Formulated from your labs and shipped in labeled pouches, updated each quarter.
- Prescription access: When labs show clinical need, licensed clinicians can prescribe TRT, GLP-1s, HRT, and more.
- Quarterly re-optimization: Every 90 days your supplements, medications, and recommendations are adjusted to your latest data.
Strengths
- The only true continuous-optimization model here
- A full panel plus three targeted follow-ups a year, with daily wearable data
- Tests, supplements, and prescribes in one place
- Available in every state but Rhode Island, including New York
Trade-offs
- Still in beta, so the product keeps changing
- Medications and supplements billed separately
- More than you need if you only want one panel
Marek Health Review
Founded in 2021, Marek Health is the specialist of this group, built around the idea that you cannot optimize what you do not measure. Its hormone diagnostics go deeper than anyone here: its three Total Health Panels cover 80+, 100+ and 130+ biomarkers, and its treatment menu spans TRT, peptides, GLP-1s, and more, prescribed through partnered licensed providers and guided by a dedicated health coach who checks in monthly. The trade-off is cost and reach. Marek does not publish a monthly coaching fee; its TRT and weight-loss pages list the program from $299 without saying how often that is billed. Lab panels cost $495 to $1,950 on top, with a $450 minimum lab purchase to start, and follow-up labs are required 6 to 12 weeks into treatment and every six months after that. Draws are done at Quest, and Marek is not available in New York, New Jersey, or Rhode Island.
- Deep hormone diagnostics: Total Health Panels of 80+, 100+ and 130+ biomarkers, with the most hormone-focused testing in this comparison.
- Broad treatment menu: TRT, peptides, GLP-1s, and other therapies through partnered licensed providers.
- Dedicated health coach: A 1:1 relationship that builds and refines your protocol around your data.
Strengths
- The most comprehensive hormone diagnostics here
- Wide treatment menu, including peptides
- Hands-on health-coach model
Trade-offs
- Highest real cost of the group
- Labs billed separately on top of coaching
- Not available in NY, NJ, or RI
Geviti Review
Geviti takes a membership approach to longevity care. The Plus membership includes its 104-biomarker Longeviti Panel twice a year (the free tier includes no testing), and its standout feature is convenience: Geviti offers at-home blood draws in major metro areas, with a walk-in lab option elsewhere. Pricing starts with a free tier that lets you upload existing lab results and use the AI, and the Plus membership is $127 per month when billed annually ($1,529 a year), more on six-month billing, with prescription access included where state rules allow. You also get a results-review video with a specialist and specialty add-ons such as the DUTCH hormone test. Plus also syncs wearable data such as sleep, HRV, recovery and glucose, includes 24/7 access to its Makor AI, and offers custom daily supplement packs at member prices. Geviti is available in 47 states, not Alaska, Rhode Island or Hawaii.
- At-home draws: A phlebotomist comes to you in many major metros, and on Plus the draw is included in the price.
- Two panels a year: Included on Plus, so you see trends, not just a snapshot.
- Prescription tier: The Plus membership includes prescription access for hormones and more, subject to state availability.
Strengths
- At-home blood draws in major metros
- Two panels a year on Plus, with wearable sync
- Prescription option on higher tier
Trade-offs
- No testing on the free tier
- Higher tiers get pricey
- Not available in AK, RI, or HI
Function Health Review
Founded in 2022 by Mark Hyman, MD, Function Health is one of the best-known names in direct-to-consumer testing, and its strength is breadth at a fair price. The membership includes a comprehensive panel of 100+ biomarkers plus a follow-up of 60+ tests three to six months later, 160+ lab tests a year, with clinician notes and a personalized action plan. In 2026 Function lowered its price to $365 per year, down from $499, which makes it a strong value for people who primarily want wide diagnostic coverage. Optional Galleri multi-cancer detection and MRI add-ons are available at extra cost.
- Broad panels: 100+ biomarkers per panel across heart, thyroid, liver, kidney, metabolic, hormone, and nutrient categories.
- Clinician notes and action plan: Every biomarker is explained, with a call for any urgent results.
- Screening add-ons: Optional cancer detection and MRI options.
Strengths
- Excellent breadth for early detection
- Strong value at $365/yr for two panels
- Optional cancer and MRI screening
Trade-offs
- Twice-a-year testing, not continuous
- No medication prescribing
- MRI, CT and cancer screening cost extra
Mito Health Review
Mito Health has moved off the one-panel model entirely. Membership is $9 a month or $99 a year, and the labs are sold at cost: the company states plainly that it profits from the membership rather than the tests. Its curated panels run from the Essential at 118 biomarkers through Core at 138 and Pro at 166, each from one blood draw plus a urine sample, up to Ultra, which adds Galleri multi-cancer screening and an at-home gut microbiome test. Members get supplements at member rates, AI health coaching through Mito Concierge with escalation to clinicians, and 1:1 consults at $39 per 30 minutes against $99 for non-members. Non-members can still buy any panel outright. Backed by well-known longevity researchers and built around personalized reference ranges adjusted for your background, it also generates a biological age estimate from your blood data. Draws are done at Quest locations, or at home where available. It is a strong choice if you want to set your own testing schedule, though ongoing tracking means buying each retest, lab testing is not offered in Rhode Island or Hawaii, and New York and New Jersey prices include a state compliance fee.
- 118 to 166 biomarkers: Curated panels of 118, 138 and 166 markers from one blood draw and a urine sample, covering heart, metabolic, hormone, and nutrient markers.
- AI plus clinician: Mito Concierge answers questions from your own results and escalates to the care team, and 1:1 consults cost $39 per 30 minutes for members.
- Biological age: A blood-derived biological age estimate, with personalized reference ranges.
Strengths
- Labs sold at cost, not marked up
- AI concierge with clinician escalation
- Biological age and personalized ranges
Trade-offs
- Testing depth, and cost, is on you to choose
- No prescriptions listed, and no stated wearable sync
- No lab testing in RI or HI
Mito Health vs Geviti: Which Should You Choose?
These two are the closest match in this group, so it is worth isolating. Both test 100+ biomarkers and both include clinician interpretation. The difference is structure. Mito Health is a $9 a month membership that sells labs at cost, with an AI advisor and consults at $39 per 30 minutes, so a thorough baseline costs whatever the panel you pick costs. Geviti's Plus membership is $127 per month billed annually and includes two panels a year and, crucially, at-home blood draws in major metros.
Choose Mito if you want to pay for testing at cost and pick your own depth, from a 118-marker panel up to 166 markers, each from one blood draw and a urine sample. Choose Geviti if you want ongoing twice-yearly testing and the convenience of a draw at home. And if you want more frequent testing layered with wearable data and the ability to actually treat what the labs find, that is where OneTwenty goes further than either.
Is OneTwenty Worth It?
At $499 per year, OneTwenty is not the cheapest entry here, but it is the only one doing continuous optimization rather than periodic testing. For that price you get one full lab panel and three targeted follow-ups a year, 22 daily device metrics from your wearables, a 24/7 AI Health Coach, custom supplements formulated from your results, and prescription access through licensed clinicians, with your protocol adjusted every 90 days. Marek goes deeper on hormones but costs far more and is unavailable in New York. Function and Mito test thoroughly but cannot treat. Geviti adds convenience and wearable sync but tests half as often.
If you only want a single snapshot, a cheaper one-time test will do the job. If you want your health actively managed and adjusted as your body changes, OneTwenty is the only option here built for that, and it works in every state except Rhode Island.
Sign up hereHow to Choose the Best Health Platform
Six questions to ask before you subscribe
- Snapshot or system? Decide whether you want a one-time baseline or a plan that updates as your numbers change.
- How often will you test? Once a year shows a snapshot. Quarterly testing shows trends, which is where most of the insight is.
- Do you want treatment, or just data? Some platforms only tell you what is off. Others can prescribe and deliver what addresses it.
- What is the real cost? Look past the headline price to separate lab fees, prescriptions, and supplements, which can add up fast on some platforms.
- Is it available where you live? Confirm state availability and regional pricing. Marek, for example, is not available in NY, NJ, or RI.
- How will you get drawn? If a lab visit is a barrier, prioritize platforms with at-home draws.
Frequently Asked Questions
Which platform is best overall?
For continuous optimization, OneTwenty leads, because it runs a full panel plus three targeted follow-ups a year, integrates daily wearable data, delivers custom supplements, prescribes medication when needed, and adjusts your protocol every 90 days. For hormone depth, Marek Health. For value, Function Health. For convenience, Geviti. For paying at cost and choosing your own panel, Mito Health.
Which is cheapest?
It depends on the model. Function Health is $365 per year for two panels, Mito Health is $9 a month with labs at cost, and Geviti's Plus membership is $127 per month billed annually, with a free tier for labs you already have. Marek Health is the most expensive once labs are added, often $2,500 or more in year one. OneTwenty is $499 per year for a full panel, three targeted follow-ups and monitoring.
Which platforms are available in New York?
Every platform here except Marek Health works in New York. OneTwenty covers every state except Rhode Island and costs $749 a year in New York and New Jersey. Function Health covers 48 states, all but Rhode Island and Hawaii, and testing in New York and New Jersey can cost more. Geviti covers 47 states, all but Alaska, Rhode Island and Hawaii. Mito Health offers no lab testing in Rhode Island or Hawaii, and its New York and New Jersey prices include a state compliance fee. Marek Health does not take orders from New York, New Jersey, or Rhode Island.
Which platforms can prescribe medication?
OneTwenty, Marek Health, and Geviti (on its Plus tier) can connect you with licensed clinicians for prescriptions such as TRT, GLP-1s, or HRT. Function Health and Mito Health are testing-only and do not prescribe.
How often should you test your biomarkers?
Once a year gives a snapshot, which is fine for general screening. Testing two to four times a year reveals trends and shows whether your changes are working. OneTwenty's full panel plus three targeted follow-ups gives the most responsive picture.
Do I still need my regular doctor?
Yes. These platforms complement primary care, not replace it. Use the data to have a more informed conversation with your physician.
Final Verdict: Which Health Platform Is Best?
The right platform depends on what you want. For the deepest hormone work, Marek Health is unmatched, if you can afford it and live outside NY, NJ, and RI. For comprehensive screening at a fair price, Function Health is the value pick. For at-home convenience, Geviti. For paying at cost and choosing your own panel, Mito Health.
But if you want a platform that does not just test you and hand you a report, one that monitors your biology continuously and adjusts your plan as your body changes, OneTwenty is the clear choice. A full lab panel plus three targeted follow-ups a year, 22 daily device metrics from your wearables, an AI health coach, custom supplement delivery, and prescription access, all in one membership, re-optimized every 90 days, available in every state except Rhode Island. No other platform here combines testing, monitoring, and treatment this completely.
Want your health actively optimized, not just measured?
OneTwenty combines one full lab panel and three targeted follow-ups a year, daily wearable monitoring, a 24/7 AI Health Coach, custom supplements, and prescription access in one membership, with your protocol adjusted every 90 days. Open beta, so you can sign up directly.
Sign up here
